{"id":13800,"date":"2025-07-21T08:55:17","date_gmt":"2025-07-21T00:55:17","guid":{"rendered":"https:\/\/li-on.biz\/?p=13800"},"modified":"2025-07-21T09:12:29","modified_gmt":"2025-07-21T01:12:29","slug":"echa%e7%99%bc%e4%bd%882%e7%a8%ae%e7%89%a9%e8%b3%aa%e7%b5%b1%e4%b8%80%e5%88%86%e9%a1%9e%e8%88%87%e6%a8%99%e7%b1%a4%e5%8f%8a16%e9%a0%85%e7%89%a9%e8%b3%aa%e6%b8%ac%e8%a9%a6%e6%8f%90%e6%a1%88%e6%84%8f","status":"publish","type":"post","link":"https:\/\/li-on.biz\/en\/echa%e7%99%bc%e4%bd%882%e7%a8%ae%e7%89%a9%e8%b3%aa%e7%b5%b1%e4%b8%80%e5%88%86%e9%a1%9e%e8%88%87%e6%a8%99%e7%b1%a4%e5%8f%8a16%e9%a0%85%e7%89%a9%e8%b3%aa%e6%b8%ac%e8%a9%a6%e6%8f%90%e6%a1%88%e6%84%8f\/","title":{"rendered":"ECHA issues call for comments on proposals for harmonized classification and labeling of two substances and testing of 16 substances"},"content":{"rendered":"

2025-07-09<\/p>\n\n\n\n

On July 7, 2025, the European Chemicals Agency (ECHA) launched a public consultation on proposals for harmonized classification and labeling (CLH) for two substances, with a deadline of September 5, 2025. On the same day, ECHA added 16 new substance testing proposals and requested public comment by August 21.<\/p>\n\n\n\n

CLH Proposal<\/strong><\/h3>\n\n\n\n
Substance name<\/strong><\/td>EC number<\/strong><\/td>CAS number<\/strong><\/td>Categories of harms for open consultation<\/strong><\/td>Consultation start time<\/strong><\/td>Feedback deadline<\/strong><\/td><\/tr>
\uff08R\uff09-2-\u7532\u57fa-5-\uff081-\u7532\u57fa\u4e59\u70ef\u57fa\uff09-2-\u74b0\u5df1\u70ef-1-\u916el-p-mentha-1(6),8-dien-2-one; (5R)-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one; l-carvone<\/td>229-352-5<\/td>6485-40-1<\/td>Explosives
Flammable liquids
Self-reactive substances and mixtures
Spontaneously igniting liquids
Self-heating substances
Substances that release flammable gases upon contact with water
Oxidizing liquids
Oral peroxides
Dermal acute toxicity
Inhalation acute toxicity
Skin corrosion\/irritation
Severe eye damage\/irritation
Skin sensitization
Reproductive cell mutagenicity
Carcinogenicity
Reproductive toxicity
Target organ toxicity - single exposure
Target organ toxicity - repeated exposure
Inhalation hazard
Hazards to aquatic environments
Hazards to the ozone layer<\/td>		07\/07\/2025<\/td>05\/09\/2025<\/td><\/tr>
\u8584\u8377\u6cb9Spearmint oil; Essential oil of Spearmint obtained from the aerial part of Mentha spicata and\/or Mentha cardiaca (Lamiaceae) obtained by distillation<\/td>–<\/td>8008-79-5<\/td>Explosives
Flammable liquids
Spontaneously igniting liquids
Self-heating substances or mixtures
Substances or mixtures that release flammable gases upon contact with water
Oxidizing liquids
Acute toxicity
Skin corrosion\/irritation
Severe eye damage\/eye irritation
Skin
Mutogenicity of germ cells
Carcinogenicity
Reproductive toxicity
Target organ toxicity\u2014single exposure
Target organ toxicity\u2014repeated exposure
Inhalation hazard
Harmful to aquatic environments
Harmful to the ozone layer<\/td>		07\/07\/2025<\/td>05\/09\/2025<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

The CLH process aims to ensure consistency and transparency in hazard information about chemicals across Europe. The process involves assessing the hazards of chemical substances, proposing corresponding classification and labelling, collecting public comments, and finally reviewing and recommending by ECHA's Risk Assessment Committee (RAC).<\/p>\n\n\n\n

https:\/\/echa.europa.eu\/harmonised-classification-and-labelling-consultation<\/a><\/p>\n\n\n\n

Substance Testing Proposal<\/strong><\/h3>\n\n\n\n
Substance name<\/td>EC number<\/td>CAS number<\/td>Information submission deadline<\/td>Propose hazard endpoints for vertebrate animal testing.<\/td><\/tr>
\u4e59\u919adiethyl ether<\/td>200-467-2<\/td>60-29-7<\/td>21\/08\/2025<\/td>7.8.1 Reproductive toxicity<\/td><\/tr>
4\uff08\u6216 5\uff09-\u7532\u57fa 1H-\u82ef\u4e26\u4e09\u5511Methyl-1h-benzotriazole<\/td>249-596-6<\/td>29385-43-1<\/td>21\/08\/2025<\/td>7.8.2 Developmental toxicity\/teratogenicity || Note: The proposed tests involve 5-methyl-1h-benzotriazole (EC number 205-265-8) and 4-methyl-1h-benzotriazole (EC number 249-921-1).<\/td><\/tr>
N-\uff082-\u4e59\u57fa\u5df1\u57fa\uff09-1-[[2-\u7532\u57fa-4-[\uff082-\u7532\u57fa\u82ef\u57fa\uff09\u5076\u6c2e]\u82ef\u57fa]\u5076\u6c2e]-2-\u7f8b\u80faN-(2-ethylhexyl)-1-[[2-methyl-4-[(2-methylphenyl)azo]phenyl]azo]naphthalen-2-amine<\/td>260-124-8<\/td>56358-09-9<\/td>21\/08\/2025<\/td>7.6.2 In vivo genotoxicity<\/td><\/tr>
\u78fa\u5316\u690d\u7269\u6cb9\uff0c\u9209\u9e7dOils, vegetable, sulfonated, sodium salts<\/td>307-044-2<\/td>97489-04-8<\/td>21\/08\/2025<\/td>6.1.2 Long-term toxicity to fish || Note: It is recommended to test the reaction products of oxidized fish oil fatty acid glycerides with sodium bisulfite (EC No.: 307-037-4).<\/td><\/tr>
\u4e09\u6c1f\u92c5\u9178\u9240Potassium trifluorozincate<\/td>237-537-7<\/td>13827-02-6<\/td>21\/08\/2025<\/td>6.1.2 Long-term toxicity to fish<\/td><\/tr>
\u5c0d\u58ec\u57fa\u915a\u3001\u7532\u919b\u8207\u4e8c\u4e59\u9187\u80fa\u53cd\u61c9\u7522\u7269\uff08\u4e19\u6c27\u57fa\u5316\uff09Reaction product of p-nonylphenol, formaldehyde and diethanolamine, propoxylated<\/td>701-426-6<\/td>–<\/td>21\/08\/2025<\/td>6.1.2 Long-term toxicity to fish<\/td><\/tr>
\u7532\u57fa\u82ef\u4e26\u4e09\u5511\u9209Sodium 4(or 5)-methyl-1H-benzotriazolide<\/td>265-004-9<\/td>64665-57-2<\/td>21\/08\/2025<\/td>7.8.2 Developmental toxicity\/teratogenicity || Note: The proposed tests involve 5-methyl-1h-benzotriazole (EC number 205-265-8) and 4-methyl-1h-benzotriazole (EC number 249-921-1).<\/td><\/tr>
7,7′-\uff08\u7fb0\u57fa\u4e8c\u4e9e\u6c28\u57fa\uff09\u96d9[4-\u7fa5\u57fa-3-[\uff086-\u78fa\u9178\u57fa-2-\u8418\u57fa\uff09\u5076\u6c2e]-2-\u8418\u78fa \u9178\u56db\u9209Tetrasodium 7,7′-(carbonyldiimino)bis[4-hydroxy-3-[(6-sulphonato-2-naphthyl)azo]naphthalene-2-sulphonate]<\/td>249-171-5<\/td>28706-25-4<\/td>21\/08\/2025<\/td>6.1.2 Long-term toxicity to fish<\/td><\/tr>
[[\u4e8c\uff082-\u4e59\u57fa\u5df1\u57fa\uff09\u6c27]\u4e8c\u786b\u4ee3\u786b\u9178\u57fa] \u4e01\u4e8c\u9178\u4e8c\u4e01\u916fDibutyl [[bis[(2-ethylhexyl)oxy]phosphinothioyl]thio]succinate<\/td>270-220-1<\/td>68413-48-9<\/td>21\/08\/202521\/08\/2025<\/td>7.5.1 Repeated-dose toxicity: oral 7.8.2 Developmental toxicity\/teratogenicity<\/td><\/tr>
N-\u82ef\u57fa\u82ef\u80fa\u82072,4,4-\u4e09\u7532\u57fa\u620a\u70ef\u7684\u53cd\u61c9\u7522\u7269Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene<\/td>270-128-1<\/td>68411-46-1<\/td>21\/08\/202521\/08\/202521\/08\/2025<\/td>6.1.2 Long-term toxicity to fish 7.8.2 Developmental toxicity\/teratogenicity (species: rat) 7.8.2 Developmental toxicity\/teratogenicity (species: rabbit)<\/td><\/tr>
2,2′-\u6c27\u57fa\u4e8c\uff08N\uff0cN-\u4e8c\u7532\u57fa\u4e59\u80fa\uff09N,N,N’,N’-tetramethyl-2,2′-oxybis(ethylamine)<\/td>221-220-5<\/td>3033-62-3<\/td>21\/08\/202521\/08\/202521\/08\/2025<\/td>6.1.2 Long-term toxicity to fish 7.8.1 Reproductive toxicity 7.8.2 Developmental toxicity\/teratogenicity<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

According to REACH regulations, before implementing Annexes IX and X (corresponding to registered tonnages of 100-1000 t\/y and above), registrants must submit a testing proposal (TP). After the public comment period, ECHA will finalize the testing requirements based on the feedback and the substance's characteristics. Through public comment, ECHA will refine the safety assessment and revise the testing requirements based on the feedback. Registrants are required to conduct these tests and update safety information to ensure the safe use of chemicals and promote sustainable development of the industry.<\/p>\n\n\n\n

https:\/\/echa.europa.eu\/information-on-chemicals\/testing-proposals\/current<\/a><\/p>","protected":false},"excerpt":{"rendered":"

2025-07-09 2025\u5e747\u67087\u65e5\uff0c\u6b50\u6d32\u5316\u5b78\u54c1\u7ba1\u7406\u5c40\uff08ECHA\uff09\u5c312\u7a2e\u7269\u8cea\u7684\u7d71\u4e00\u5206\u985e\u8207\u6a19\u7c64\uff08CLH\uff09\u63d0\u6848 […]<\/p>","protected":false},"author":104,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[79],"tags":[],"class_list":["post-13800","post","type-post","status-publish","format-standard","hentry","category-echa"],"acf":[],"yoast_head":"\nECHA\u767c\u4f482\u7a2e\u7269\u8cea\u7d71\u4e00\u5206\u985e\u8207\u6a19\u7c64\u53ca16\u9805\u7269\u8cea\u6e2c\u8a66\u63d0\u6848\u610f\u898b\u5fb5\u96c6 - \u7acb\u96cd\u79d1\u6280<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ECHA\u767c\u4f482\u7a2e\u7269\u8cea\u7d71\u4e00\u5206\u985e\u8207\u6a19\u7c64\u53ca16\u9805\u7269\u8cea\u6e2c\u8a66\u63d0\u6848\u610f\u898b\u5fb5\u96c6 - 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