ECHA建議新增13項高度關切物質

ECHA (European Chemical Agency) has submitted 13 new proposals for substances of very high concern (SVHCs). ECHA has opened a 45-day public consultation period, which ends on April 12, 2012.

SVHCs refer to all substances that comply with Article 57 of the REACH Regulation and are mutagenic, carcinogenic, or reproductively toxic (CMR). Specifically, the following four substances are considered potential SVHCs if present at a concentration of 0.1% wt/wt or higher of Michler's ketone (EC Number: 202-027-5) or Michler's base (EC Number: 202-959-2).

Basic Violet 3

Basic Blue 26

Solvent Blue 4

4,4'-Di(N,N-dimethylamino)diphenyl ketone

Comments submitted should include substance identification information, and information on the tonnage used per instance, substance release levels, and intended use of the exposed substances is also welcome. Manufacturers can also provide information on safe alternatives and technologies, as well as supply chain structures. ECHA will consider this information when drafting the SVHCs list (Annex 14). At the request of the European Commission, Belgium, Poland, Finland, Germany, and ECHA have submitted proposals regarding Substances of Very High Concern (SVHCs). The substance names, reasons for being recommended as SVHCs, and usage information are now available on the ECHA website. Comments must be submitted using the designated web format. To date, 73 SVHCs have been included in the candidate list. Suppliers whose mixtures and finished products contain substances from this list will be subject to new regulations.

List of substances proposed for inclusion in the SVHC, the reasons for the proposal, and their potential uses

Substance name	EC No.	CAS No.	SVHC characteristics	Possible uses*
1,2-bis(2-methoxyethoxy)ethane(TEGDME; triglyme)三乙二醇二甲醚	203-977-3	112-49-2	Reproductive toxicity	Primarily used as a solvent or in the production of processing aids and industrial chemical formulations. Secondarily used in brake fluid and vehicle repair.
1,2-dimethoxyethane; ethylene glycol dimethyl ether (EGDME)乙二醇二甲醚	203-794-9	110-71-4	Reproductive toxicity	It is mainly used as a solvent or in the production of processing aids and industrial chemical formulations, including electrolytes used in lithium batteries.
Diboron trioxide氧化硼	215-125-8	1303-86-2	Reproductive toxicity	It is widely used in a variety of applications, such as glass, fiberglass, tubing, ceramics, flame retardants, catalysts, industrial fluids, metallurgy, adhesives, inks/printing, film processing solutions, cleaning agents, insecticides, and bactericides.
Formamide甲醯胺	200-842-0	75-12-7	Reproductive toxicity	Its primary use is as an intermediate. Secondary uses include as a solvent, a chemical reactant (in the pharmaceutical industry), and a laboratory chemical. This substance is also used in the agricultural chemical industry and as a plasticizer.
Lead(II)bis(methanesulfonate)甲基磺酸鉛	401-750-5	17570-76-2	Reproductive toxicity	It is mainly used in the electroplating process of electronic components (such as printed circuit boards) (including electrolytic and electroless electroplating).
TGIC(1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1 H,3H,5H)-trione)異氰尿酸三縮水甘油酯	219-514-3	2451-62-9	Mutagenicity	It is mainly used as a resin and coating hardener; it is also used in printed circuit boards, electronic insulation materials, resin modeling systems, shell materials, screen printing coatings, tools, adhesives, lining materials and plastic stabilizers.
β-TGIC (1,3,5-tris[(2Sand2R)-2,3-epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione)β型異氰尿酸三縮水甘油酯	423-400-0	59653-74-6	Mutagenicity	It is mainly used as a resin and coating hardener; it is also used in printed circuit boards, electronic insulation materials, resin modeling systems, shell materials, screen printing coatings, tools, adhesives, lining materials and plastic stabilizers.
4,4\’-bis(dimethylamino) benzophenone (Michler\’s ketone)4,4\’-二(N,N-二甲胺基) 二苯基酮米其勒酮	202-027-5	90-94-8	Carcinogenicity	Triphenylmethane is an intermediate in the production of dyes and other substances. It may also be used in dye additives (photosensitizers), pigments, dry film products, and as a surface process chemical in circuit board manufacturing, research, and development.
N,N,N\’,N\’-tetramethyl-4 ,4\’-methylenedianiline (Michler\’s base)4,4\’-亞甲基雙(N,N-二甲苯胺)米其勒鹼	202-959-2	101-61-1	Carcinogenicity	It is used as an intermediate in the production of dyes and other substances. It is also used in the research and development of chemical reagents.
[4-[4,4\’-bis(dimethylamino) benzhydrylidene]cycloh exa-2,5-dien-1-ylidene]dimethylammonium chloride(C.I. Basic Violet 3)鹼性紫3	208-953-6	548-62-9	Carcinogenic	Primarily used in printing disk cartridges and for coloring paper and ink in ballpoint pens. Further applications include drying plant stains, increasing the visibility of marker liquids, microbial staining, and clinical laboratories.
[4-[[4-anilino-1-naphthy l][4-(dimethylamino)phenyl]methylene]cyclohe xa-2,5-dien-1-ylidene] dimethylammoniumchloride (C.I. Basic Blue 26)C.I. 鹼性藍26([4-[[4-苯胺基-1-萘基][4-(二甲基胺基)苯基]亞甲基]環己-2,5-二烯-1-亞基]二甲基氯化銨	219-943-6	2580-56-5	Carcinogenic	It is used in inks, cleaning agents, coatings and paper dyeing, packaging, textiles, plastic products and other types of finished products. It is also used in diagnostic and analytical applications.
α,α-Bis[4-(dimethylamino)phenyl]-4 (phenylamino)naphthalene-1-methanol (C.I. Solvent Blue 4)C.I. 溶劑藍4α,α-雙[4-(二甲基胺基)苯基]-4-(苯基胺基)-1-萘甲醇	229-851-8	6786-83-0	Carcinogenic	It is mainly used in the manufacture of printing and writing inks, paper dyeing, and windshield washer fluids.
4,4\’-bis(dimethylamino)-4\’\’-(methylamino)trityl alcoholC.I. 溶劑紫8(4,4’-雙(二甲基胺基)-4’’-(甲基胺基)三苯甲基醇)	209-218-2	561-41-1	Carcinogenic	It is used in the manufacture of writing ink, and may also be used in the manufacture of other inks and the dyeing of various materials.

Sources: ECHA(2012-02-28) (Compiled by PIDC)